445298-98-6

Basic information

• Product Name: Butanoic acid, 2-bromo-, (1S,2S)-2-(dimethylamino)-1-phenylpropyl ester
• CAS NO: 445298-98-6
• Molecular Formula: C15H22BrNO2
• Molecular Weight: 328.249
• Mol File: 445298-98-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 2-bromo-, (1S,2S)-2-(dimethylamino)-1-phenylpropyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-bromo-, (1S,2S)-2-(dimethylamino)-1-phenylpropyl ester(445298-98-6)
• EPA Substance Registry System: Butanoic acid, 2-bromo-, (1S,2S)-2-(dimethylamino)-1-phenylpropyl ester(445298-98-6)

Safety Data

• Hazardous Substances Data: 445298-98-6(Hazardous Substances Data)

Upstream product

• 80-58-0 2-Bromobutyric acid 
• 1201-56-5 (1S,2S)-N-Methylpseudoephedrine 

Downstream Products

• 1327310-78-0 1,4-dibenzyl-(S)-3-ethyl-2-piperazinone 
• 1327310-87-1 1,4-dibenzyl-(R)-3-ethyl-2-piperazinone 

Relevant articles and documents

Dynamic thermodynamic resolution of N-methylpseudoephedrine α-bromo esters for asymmetric syntheses of α-hydroxy carboxylic acid derivatives

An example of dynamic thermodynamic resolution in the nucleophilic substitution reactions of α-bromo esters with an oxygen nucleophile is described. Temperature controlled epimerization-substitution sequence provides a practical protocol for the preparation of highly enantioenriched α-hydroxy carboxylic acid derivatives up to 72% yield with 99:1 er.