445302-16-9 Usage
Type of Compound
Heterocyclic carboxylic acid derivative
Structure
Contains a trifluoromethylphenyl group attached to an imidazole ring with a carboxylic acid group at the 4-position
Applications
a. Building block in the synthesis of pharmaceutical compounds and agrochemicals
b. Acts as a ligand for metal catalysts
c. Potential inhibitor of enzymes
Trifluoromethyl Group
Enhances lipophilicity and bioavailability, making it useful in drug design and development
Imidazole Moiety
Contributes to potential biological activity and medicinal properties
Importance in Synthesis
Often used as a building block due to its ability to act as a ligand and potential enzyme inhibition properties
Biological Significance
The imidazole ring and carboxylic acid group provide potential for biological activity and medicinal properties
Chemical Properties
a. Acidic due to the presence of the carboxylic acid group
b. Lipophilic due to the trifluoromethyl group
c. Capable of forming coordination complexes with metal catalysts due to the imidazole ring and carboxylic acid group
Physical Properties
a. Solid-state structure dependent on the method of synthesis and purification
b. Solubility in organic solvents, such as dimethyl sulfoxide (DMSO) or methanol, due to its lipophilic nature
c. Stability under various conditions, depending on the specific application and formulation
Safety and Handling
a. Use appropriate personal protective equipment (PPE) when handling, such as gloves and safety goggles
b. Store in a well-closed container, away from heat, light, and moisture
c. Dispose of according to local regulations and guidelines for chemical waste management
Check Digit Verification of cas no
The CAS Registry Mumber 445302-16-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,5,3,0 and 2 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 445302-16:
(8*4)+(7*4)+(6*5)+(5*3)+(4*0)+(3*2)+(2*1)+(1*6)=119
119 % 10 = 9
So 445302-16-9 is a valid CAS Registry Number.
445302-16-9Relevant academic research and scientific papers
Imidazole derivatives
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, (2008/06/13)
Novel imidazole derivatives are disclosed. These compounds have a good affinity to the NMDA (N-methyl-D-aspartate)-receptor subtype selective blockers, which have a key function in modulating neuronal activity and plasticity which makes them key players in mediating processes underlying development of CNS as well as learning and memory formation. These compounds are useful in the control or treatment of diseases mediated by this receptor.
