445423-72-3

Upstream product

• 22406-33-3 4-sulfanyl-2H-chromen-2-one 
• 4200-22-0 1-(4-chlorophenyl)oxy-4-chloro-but-2-yne 

Downstream Products

• 457646-64-9 3-(5-chloro-2-hydroxy-phenyl)-4-methylene-3,4-dihydro-2H-thiopyrano[3,2-c]chromen-5-one 
• 445423-78-9 4-[4-(4-chloro-phenoxy)-but-2-yne-1-sulfinyl]-chromen-2-one 
• 457646-57-0 4-(4-chloro-phenoxymethyl)-2H-thiopyrano[3,2-c]chromen-5-one 

Relevant academic research and scientific papers

Studies in sigmatropic rearrangement: Synthesis of a [6,6]pyranothiopyran ring system by sequential claisen rearrangement and pyridine hydrotribromide mediated regioselective "6-Endo"cyclization

(Matrix presented) 4-(4′-Aryloxybut-2′-ynylthio)[1]benzopyran-2-ones are refluxed in chlorobenzene to afford 4-aryloxymethylthiopyrano[3,2-c][1]benzopyran-5(2H)-ones which are subsequently subjected to heating in o-dichlorobenzene in the presence of N,N-d

Studies on sulfoxide rearrangements: Regioselective synthesis of 3-(aryloxyacetyl)-2,3-dihydrothieno[3,2-c][1]benzopyran-4-ones

Hitherto unreported 3-(aryloxyacetyl)-2,3-dihydrothieno[3,2-c][1] benzopyran-4-ones 5a-f were synthesised in 70-75% yields by the application of the sulfoxide rearrangement of 4-(4-aryloxybut-2-ynylthio)[1]benzopyran-2-ones 4a-f. The substrates 4a-f were