445433-08-9

Basic information

• Product Name: (R)-((1S,2S,4S,5R)-5-{3-[(Z)-Benzylimino]-propyl}-1-aza-bicyclo[2.2.2]oct-2-yl)-quinolin-4-yl-methanol
• Synonyms: (R)-((1S,2S,4S,5R)-5-{3-[(Z)-Benzylimino]-propyl}-1-aza-bicyclo[2.2.2]oct-2-yl)-quinolin-4-yl-methanol
• CAS NO: 445433-08-9
• Molecular Weight: 413.563
• Mol File: 445433-08-9.mol

Chemical Properties

• CAS DataBase Reference: (R)-((1S,2S,4S,5R)-5-{3-[(Z)-Benzylimino]-propyl}-1-aza-bicyclo[2.2.2]oct-2-yl)-quinolin-4-yl-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-((1S,2S,4S,5R)-5-{3-[(Z)-Benzylimino]-propyl}-1-aza-bicyclo[2.2.2]oct-2-yl)-quinolin-4-yl-methanol(445433-08-9)
• EPA Substance Registry System: (R)-((1S,2S,4S,5R)-5-{3-[(Z)-Benzylimino]-propyl}-1-aza-bicyclo[2.2.2]oct-2-yl)-quinolin-4-yl-methanol(445433-08-9)

Safety Data

• Hazardous Substances Data: 445433-08-9(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 445433-05-6 10,11-dihydrocinchonidine-11-carbaldehyde 
• 485-71-2 Cinchonidin 

Relevant articles and documents

Highly selective hydroformylation of the Cinchona alkaloids

The four naturally occurring cinchona alkaloids were subjected to hydroformylation to create an extra functional group that allows immobilization. Cinchonidine, quinine, and quinidine, could be hydroformylated with virtually complete terminal selectivity, using a rhodium/tetraphosphite catalyst. The cinchonidine aldehyde was reduced to the alcohol and subjected to reductive amination with benzylamine.