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(4S,6S)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-4-(4-fluoro-phenyl)-piperidin-2-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

445474-58-8

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445474-58-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 445474-58-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,5,4,7 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 445474-58:
(8*4)+(7*4)+(6*5)+(5*4)+(4*7)+(3*4)+(2*5)+(1*8)=168
168 % 10 = 8
So 445474-58-8 is a valid CAS Registry Number.

445474-58-8Relevant academic research and scientific papers

Stereocontrolled synthesis of a prototype library of enantiopure 2,4-disubstituted 4-aryl-6-piperidinones and piperidines

Hanessian, Stephen,Van Otterlo, Willem A.L,Nilsson, Ingemar,Bauer, Udo

, p. 1995 - 1998 (2007/10/03)

Addition of a set of aryl cuprates to N-Boc O-TBDPS 2-hydroxymethyl 3,4-unsaturated 6-piperidinones affords syn-adducts in preference to anti when mixed Grignard-cuprates are used. Aryllithio cuprates give more of the anti-isomer in some cases. A library of 2-hydroxymethyl carbamates (27 compounds) and 2-hydroxymethyl aryl ethers and thioethers (19 compounds) was generated from a selection of 4-aryl-6-piperidinones, and some were further reduced to the corresponding piperidines (9 compounds).

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