446253-69-6Relevant articles and documents
CHEMICAL SYNTHESIS OF REAGENTS FOR PEPTIDE COUPLING
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Page 22, (2010/02/05)
The present invention provides improved methods for synthesis of phosphinothiol reagents, as well as novel protected reagents, for use in formation of amide bonds, and particularly for peptide ligation. The invention provides phosphineborane complexes useful as reagents in the formation of amide bonds, particularly for the formation of an amide bond between any two of an amino acid, a peptide, or a protein.