446312-32-9

Upstream product

• 328236-46-0 3,5-dimethyl-4-(3'-isopropyl-4'-O-methoxymethylbenzyl)-O-triisopropylsilylphenol 
• 79887-10-8 1-ethynyl-4-(n-pentyl)benzene 
• 446312-30-7 triisopropyl-{4-[3-isopropyl-4-methoxymethoxy-5-(4-pentylphenylethynyl)benzyl]-3,5-dimethylphenoxy}silane 

Downstream Products

• 446312-34-1 {4-[3-isopropyl-4-methoxymethoxy-5-(4-pentylphenylethynyl)benzyl]-3,5-dimethylphenoxy}acetic acid tert-butyl ester 
• 446312-36-3 {4-[4-hydroxy-3-isopropyl-5-(4-pentyl-phenylethynyl)-benzyl]-3,5-dimethyl-phenoxy}-acetic acid tert-butyl ester 

Relevant academic research and scientific papers

Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment

Recent efforts have focused on the design and synthesis of thyroid hormone (T3) antagonists as potential therapeutic agents and chemical probes to understand hormone-signaling pathways. We previously reported the development of novel first-gene