447459-55-4Relevant academic research and scientific papers
Optimization of triaryl bis-sulfones as cannabinoid-2 receptor ligands
Lavey, Brian J.,Kozlowski, Joseph A.,Shankar, Bandarpalle B.,Spitler, James M.,Zhou, Guowei,Yang, De-Yi,Shu, Youheng,Wong, Michael K.C.,Wong, Shing-Chun,Shih, Neng-Yang,Wu, Jie,McCombie, Stuart W.,Rizvi, Razia,Wolin, Ronald L.,Lunn, Charles A.
, p. 3760 - 3764 (2008/02/12)
Structure-activity relationship on our recently reported triaryl bis-sulfone class of cannabinoid-2 (CB2) receptor selective inverse agonists was explored. Modifications to the methane sulfonamide, substitutions to B and C phenyl rings, and replacements o
Cannabinoid receptor ligands
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Page 34, (2008/06/13)
The invention relates to compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmac
