447459-56-5Relevant academic research and scientific papers
Optimization of triaryl bis-sulfones as cannabinoid-2 receptor ligands
Lavey, Brian J.,Kozlowski, Joseph A.,Shankar, Bandarpalle B.,Spitler, James M.,Zhou, Guowei,Yang, De-Yi,Shu, Youheng,Wong, Michael K.C.,Wong, Shing-Chun,Shih, Neng-Yang,Wu, Jie,McCombie, Stuart W.,Rizvi, Razia,Wolin, Ronald L.,Lunn, Charles A.
, p. 3760 - 3764 (2007)
Structure-activity relationship on our recently reported triaryl bis-sulfone class of cannabinoid-2 (CB2) receptor selective inverse agonists was explored. Modifications to the methane sulfonamide, substitutions to B and C phenyl rings, and replacements o
