447463-75-4Relevant articles and documents
Tetrathiatriarylmethyl radicals conjugated to an RGD-peptidomimetic
Driesschaert, Benot,Levque, Philippe,Gallez, Bernard,Marchand-Brynaert, Jacqueline
, p. 8077 - 8084 (2014)
Tetrathiatriarylmethyl (TAM) radicals are favourite spin labels for electron paramagnetic resonance imaging (EPRI). In this work, we report a straightforward synthesis of new TAM radicals bound to an Arg-Gly-Asp (RGD)-peptido-mimetic known to be a cell-targeting agent. These new radicals are stable in solution, and sensitive to oxygen, and their experimental EPR data is consistent with density functional theory (DFT) calculations.