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2-(4-fluoro-phenoxy)-benzoic acid methyl ester is a synthetic organic compound characterized by its molecular formula C15H13FO3. 2-(4-fluoro-phenoxy)-benzoic acid methyl ester features a benzoic acid structure with a methyl ester group attached to the carboxylic acid, enhancing its solubility in organic solvents. The presence of a 4-fluoro-phenoxy group provides a fluorine atom at the para position of the phenyl ring, which can significantly influence the compound's electronic properties and potentially its biological activity. This chemical is often used in the synthesis of pharmaceuticals and agrochemicals due to its ability to modulate the activity of various biological targets. Its specific applications may include the development of new drugs or pesticides, where the fluorine atom can impart unique properties such as increased lipophilicity or metabolic stability.

448-24-8

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448-24-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 448-24-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,4 and 8 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 448-24:
(5*4)+(4*4)+(3*8)+(2*2)+(1*4)=68
68 % 10 = 8
So 448-24-8 is a valid CAS Registry Number.

448-24-8Relevant academic research and scientific papers

A photoredox-neutral Smiles rearrangement of 2-aryloxybenzoic acids

Gonzalez-Gomez, Jose C.,Ramirez, Nieves P.,Lana-Villarreal, Teresa,Bonete, Pedro

, p. 9680 - 9684 (2017)

We report on the use of visible light photoredox catalysis for the radical Smiles rearrangement of 2-aryloxybenzoic acids to obtain aryl salicylates. The method is free of noble metals and operationally simple and the reaction can be run under mild batch or flow conditions. Being a redox neutral process, no stoichiometric oxidants or reductants are needed.

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