448-65-7

Usage

InChI:InChI=1/C30H30N4O4/c1-15-9-20-12-25-17(3)21(5-7-29(35)36)27(33-25)14-28-22(6-8-30(37)38)18(4)26(34-28)13-24-16(2)10-19(32-24)11-23(15)31-20/h9-14,31,34H,5-8H2,1-4H3,(H,35,36)(H,37,38)/b19-11-,20-12-,23-11-,24-13-,25-12-,26-13-,27-14-,28-14-

Upstream product

• 21007-21-6 deuterohemin 
• 10589-94-3 deuteroporphyrin IX dimethyl ester 

Downstream Products

• 10589-94-3 deuteroporphyrin IX dimethyl ester 
• 14326-24-0 deuteroporphyrinatocopper(II) 
• 58537-78-3 2,4-disulfonic-1,3,5,8-tetramethylporphin-6,7-dipropanoic acid 

Relevant academic research and scientific papers

Rapid aerobic oxidation of alcohols to carbonyl compounds with dioxygen using metallodeuteroporphyrin dimethyl esters as catalysts in the presence of isobutylaldehyde

A facile biomimetic method for rapid oxidation of alcohols to carbonyl compounds using dioxygen as the primary oxidant catalyzed by metallodeuteroporphyrin dimethyl ester [M(DPDME)] in acetonitrile as the reaction solvent and isobutylaldehyde as cocatalyst has been investigated. Among the M(DPDME) catalysts, where M = Fe(III), Co(II), Mn(III), Ni(II), Cu(II), and Zn(II), cobalt porphyrin was found to be the most active and effective catalyst. The catalytic system was widely used in the oxidation of various alcohols and especially exhibited excellent activity for oxidation of aromatic alcohols under mild conditions. Moreover, M(DPDME) was prepared from an improved facile method by chemical modification of natural hemin and an alternative mechanism for the aerobic oxidation of alcohols has been proposed and discussed.

PORPHYRIN LINKED METRONIDAZOLE AGAINST GUM DISEASE: PORPHYROMONAS GINGIVALIS

The present invention relates generally to targeted molecular agents (TMAs) directed to a particular organism or group of organisms and uses thereof. More particularly, the present invention provides TMAs having a targeting moiety which comprises a natural or induced auxotrophic requirement of the particular organism as a vehicle for directing an agent linked to the moiety to be delivered to the target organism. The TMAs of the present invention are useful for targeting molecules such as antimicrobial agents and diagnostic agents to selected organisms.

Efficient functionalization of porphyrin derivatives possessing sulfonic acid groups

A method for preparing functionalized derivatives of organic or inorganic compounds and tetrapyrrolic compounds in particular, all of which compounds have at least one sulfonic acid group, by first preparing a sulfonyl halide intermediate of the compound then reacting the intermediate with a second compound having a reactive hydroxyl or amine group to yield the desired sulfonylamide or sulfonic esters thereof. The method may be used to produce a variety of photosensitive compounds having different functionality. For example, sulfonamide or sulfonic ester reaction products of the tetrapyrrolic compounds or other photosensitive organic molecules may exhibit an enhanced ability to localize at a particular target site for phototherapy. The method provides means for altering the functionality of sulfonic acid-containing photosensitive compounds to produce derivatives thereof which may aid in the detection and/or phototherapy of diseased sites or provide functionality having enhanced affinity and exhibiting improved binding to site specific receptors within a diseased target tissue such that the therapy is improved.