448-70-4

Usage

General Description

2,8,12,18-Tetraethyl-3,7,13,17-tetramethyl-21H,23H-porphyrin is a chemical compound with a highly symmetric and cyclic structure. It consists of four pyrrole rings linked by methine bridges, forming a macrocyclic structure known as a porphyrin. 2,8,12,18-Tetraethyl-3,7,13,17-tetramethyl-21H,23H-porphyrin is dervived from heme, a molecule found in hemoglobin and myoglobin. Porphyrins play a crucial role in biologically important processes such as oxygen transport and enzymatic catalysis. In addition, they have been widely studied for their potential applications in organic synthesis, medicinal chemistry, and materials science. The presence of four ethyl groups and four methyl groups in specific positions of the porphyrin core gives 2,8,12,18-Tetraethyl-3,7,13,17-tetramethyl-21H,23H-porphyrin unique properties and makes it suitable for various chemical and biological applications.

InChI:InChI=1/C32H38N4/c1-9-21-17(5)25-13-26-19(7)23(11-3)31(35-26)16-32-24(12-4)20(8)28(36-32)14-27-18(6)22(10-2)30(34-27)15-29(21)33-25/h13-16,33,35H,9-12H2,1-8H3/b25-13-,26-13-,27-14-,28-14-,29-15-,30-15-,31-16-,32-16-

Upstream product

• 108869-78-9 bis(4-ethyl-3-methyl-2-pyrryl)(2,5-dimethoxyphenyl)methane 
• 131353-85-0 5-(4-Bromophenyl)-2,8-diethyl-3,7-dimethyldihydrodipyrrin 
• 133580-52-6 (3-Bromphenyl)bis(4-ethyl-3-methyl-2-pyrryl)methan 
• 94827-38-0 4-ethyl-5-methoxymethyl-3-methylpyrrole-2-carboxylic acid 
• 52853-18-6 N,N-diethyl(methylene)ammonium chloride 
• 129618-97-9 bis(4-ethyl-3-methyl-2-pyrryl)(4-(hydroxymethyl)phenyl)methane 
• 92415-30-0 bis(3-ethyl-4-methyl-1H-pyrrol-2-yl)methane 
• 87597-43-1 α,α-<4,4'-diethyl-3,3'-dimethyl-2,2'-dipyrryl>toluene 
• 87597-44-2 <5,5'-bis(methoxymethyl)-4,4'-dimethyl-3,3'-diethyl-2,2'-dipyrryl>methene hydrobromide 
• 90744-34-6 diacetamido-2,6 benzaldehyde 
• 606-31-5 2,6-dinitrobenzaldehyde 

Relevant academic research and scientific papers

Synthesis, self-assembling properties and incorporation of carbohydrate-substituted porphyrins into cell membrane models

A general and very efficient synthesis of new carbohydrate-substituted porphyrins is described. Reaction of porphyrin 6 with different glycosyl imidates 7a-g leads to the formation of carbohydrate-substituted porphyrins 9a-g in good yield. Subsequent demetallation and removal of the carbohydrate protection groups leads to the metal-free compounds 11a-g. In aqueous solution, compounds 11a-g tend to form defined water-soluble aggregates in a self-assembling process. In methanol/water mixtures the aggregation process depends upon the configuration of the anomeric carbon in the carbohydrate moiety. The porphyrinic aggregates are characterized by strong exciton splitting in the Soret absorption spectrum and a red shift for all absorption bands. Interaction of the porphyrinic aggregates with phosphatidylethanolamine and DMPC liposomes leads to very efficient incorporation of mainly monomeric porphyrins 11a-g into the liposomes, as was indicated by very large binding constants. At low liposome concentrations noncovalent porphyrin dimers were detected.

Cyclotetramerization of modified Knorr pyrroles into porphyrins. A reinvestigation.

The tetramerization of 3-ethyl-4-methyl-5-(methoxymethyl)pyrrole derivatives into is reinvestigated.This study demonstaretes that in most cases the starting material were misidentified and that, under controlled conditions, the pyrrole redistribution reac

Condensation of 3,3'-Diethyl-4,4'-Dimethyl-2,2'-Dipyrrylmethane with Substituted Benzaldehydes

The condensation of dipyrrylmethane 1b with o-nitrobenzaldehyde furnishes, upon oxidation with chloranil, 5,15-di(o-nitrophenyl)porphyrin 4b in 45percent yield and condensation of the same dipyrrylmethane with 2,6-dinitro or 2,6-diacetamidobenzaldehyde affords unexpectedly octaalkylporphyrin 5 (15-20percent yield) and monoaryl porphyrin 6 (2percent yield). Key words: arylporphyrin / porphyrin

Synthesis of 5,15-Diaryl-Substituted Porphyrins by Aminomethylation of Bis(4-ethyl-3-methyl-2-pyrryl)phenylmethanes

The synthesis of unsymmetrically diarylsubstituted porphyrins 11a-g (yields 5-19 percent) is described.Aminomethylation of dipyrromethane 6a with Mannich reagent 9 in acetonitrile leads to the intermediate 10, which is directly converted into the porphyri