448235-02-7Relevant academic research and scientific papers
Primaquine-pyrimidine hybrids: Synthesis and dual-stage antiplasmodial activity
Kaur, Hardeep,Machado, Marta,De Kock, Carmen,Smith, Peter,Chibale, Kelly,Prudêncio, Miguel,Singh, Kamaljit
, p. 266 - 273 (2015)
Abstract A series of novel pyrimidine-primaquine hybrids were synthesized and their effectiveness against the blood and liver stages of malaria parasites was evaluated. The hybrids displayed enhanced liver stage in vitro activity against P. berghei liver
Quinolinium Chlorochromate: An Excellent Reagent for N3-C4 Dehydrogenation of Dihydropyrimidinones and their Antifungal Evaluation
Kaur, Jaspal,Utreja, Divya,Verma, Vibha
, p. 11 - 20 (2021/06/12)
To enhance the efficacy of 3,4-dihydropyrimidin-2-ones (DHPMs) as an antifungal agent, their dehydrogenated derivatives, i.e., pyrimidin-2-ones were synthesized employing quinolinium chlorochromate as an oxidizing agent. The synthesized compounds were scr
