448238-56-0Relevant academic research and scientific papers
Direct amination of phenols under metal-free conditions
Yu, Jianzhong,Wang, Yongtao,Zhang, Peizhi,Wu, Jun
, p. 1448 - 1454 (2013)
Herein, we disclose the metal-free synthesis of arylamines via the direct amination of phenols using aminating reagents. This reaction procedure uses easy accessible aminating reagents and provides a versatile synthetic route to a broad range of arylamines with various functionalities in good to excellent yield. By using a two-step route of amination and oxidative coupling reaction, we synthesized three naturally occurring carbazole alkaloids: murrayafoline A, mukonine, and clausenine from two commercially available phenols. Georg Thieme Verlag Stuttgart · New York.
