448294-94-8Relevant academic research and scientific papers
Stereoselective synthesis of 3-alkylsulfinylmethylisoxazolines and their use as chiral nucleophiles in the chain elongation of 2,3-O-isopropylidene-D-glyceraldehyde
Lopez-Sastre,Martin-Ramos,Rodriguez-Amo,Santos-Garcia,Sanz-Tejedor
, p. 4791 - 4803 (2007/10/03)
The reaction of racemic 3-methylisoxazolines and enantiomerically pure (RS)- and (SS)-methanesulfinates and (RS)- and (SS)-ethanesulfinates of 1,2:5,6-di-O-isopropylidene-D-glucofuranose allows enantiomerically pure 3-alkylsulfinylmethylisoxazolines with both absolute configurations at sulfur to be obtained. One of these has been used as a chiral nucleophile in the four carbon homologation of 2,3-O-isopropylidene-D-glyceraldehyde 17.
