4487-43-8

Upstream product

• 87762-28-5 6-(2-Hydroxy-2,2-diphenyl-ethyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid tert-butyl ester 
• 88252-29-3 3-(N-imidazolyl-carbonyl)-6-methyl-2-pyridone 
• 4241-27-4 1,2-dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile 
• 81450-67-1 1,2-dihydro-6-methyl-2-oxo-3-pyridinecarboxylic acid, t-butyl ester 
• 38116-61-9 6-Methylpyrid-2-one-3-carboxylic Acid 
• 119-61-9 benzophenone 
• 4487-42-7 3-Cyan-6-(2,2-diphenyl-2-hydroxyethyl)-2(1H)-pyridon 

Downstream Products

• 87762-26-3 6-(2,2-diphenylethenyl)-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid 

Relevant academic research and scientific papers

Functionalization of substituted 2(1H)- and 4(1H)-pyridones. III. The preparation of substituted 6-vinyl-1,2-dihydro-2-oxo- and 1,4-dihydro-4-oxo-3-pyridinecarboxylic acids through the chemistry of pyridone dianions

The synthesis of various substituted 6-vinyl-1,2-dihydro-2-oxo-3-pyridinecarboxylic acids from the dianions of 1,2-dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile and the corresponding 3-t-butyl ester is reported. The dianions were generated with LDA in THF at low temperature and reacted with various carbonyl substrates. Several conditions for the dehydration and hydrolysis of these adducts to the vinyl pyridone acids are discussed. Employing the conditions used for the 2-pyridone analogs, a series of substituted 6-vinyl-1,4-dihydro-4-oxo-3-pyridinecarboxylic acids was prepared through the new dianion of 1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxylic acid, t-butyl ester.