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[2-(di-tert-butoxy-phosphoryloxy)-1-(4-octyl-phenylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

448959-76-0

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  • [2-(di-tert-butoxy-phosphoryloxy)-1-(4-octyl-phenylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester

    Cas No: 448959-76-0

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448959-76-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 448959-76-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,8,9,5 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 448959-76:
(8*4)+(7*4)+(6*8)+(5*9)+(4*5)+(3*9)+(2*7)+(1*6)=220
220 % 10 = 0
So 448959-76-0 is a valid CAS Registry Number.

448959-76-0Downstream Products

448959-76-0Relevant articles and documents

ORALLY AVAILABLE SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONISTS AND ANTAGONISTS

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Page/Page column 99-101, (2008/06/13)

The present invention relates to S1P analogs that have activity as S1Preceptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. The compounds have the general structure (I) wherein R11 is C5-C18 alkyl or C5-C18 alkenyl; Q is selected from the group consisting of C3-C6 optionally substituted cycloalkyl, C3-C6 optionally substituted heterocyclic, C3-C6 optionally substituted aryl C3-C6 optionally substituted heteroaryl and; R2 is selected from the group consisting of H, C1-C4 alkyl, (C1-C4 alkyl)OH and (C1-C4 alkyl)NH2; R23 is H or C1-C4 alkyl, and R15 is a phosphonate ester or a phosphate ester or a pharmaceutically acceptable salt or tautomer thereof.

NOVEL LYSOPHOSPHATIDIC ACID RECEPTOR SELECTIVE ANTAGONISTS

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Page/Page column 79, (2008/06/13)

The present invention is directed to compositions comprising lysophosphatidic acid analogs and methods of using such analogs as agonist or antagonists of LPA receptor activity. In addition the invention is directed to LPA receptor agonists that vary in the degree of selectivity at individual LPA receptors (i.e. LPA1, LPA2 and LPA3). More particularly the present invention is directed to LPA analogs wherein the glycerol is replaced with ethanolamine and a variety of substitutions have been linked at the second carbon atom.

Synthesis of Para-alkyl aryl amide analogues of sphingosine-1-phosphate: Discovery of potent S1P receptor agonists

Clemens, Jeremy J.,Davis, Michael D.,Lynch, Kevin R.,Macdonald, Timothy L.

, p. 3401 - 3404 (2007/10/03)

Sphingosine-1-phosphate (S1P) is a biologically active lysophospholipid with the capacity to induce a broad range of cellular responses via its interaction with the S1P family of G-protein coupled receptors. This report describes the synthesis of several

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