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Indaconitine, a toxic alkaloid compound, is found in plants of the Aconitum (monkshood) genus. It acts as a potent voltage-gated sodium channel blocker, influencing nerve and muscle functions. Known for its high toxicity, Indaconitine can lead to symptoms such as dizziness, nausea, vomiting, and in severe cases, heart and respiratory failure. Historically utilized in traditional Chinese medicine for its analgesic and anti-inflammatory properties, its use in modern medicine has been discontinued due to its dangerous nature. Indaconitine is now a controlled substance with strict regulatory measures in place.

4491-19-4

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4491-19-4 Usage

Uses

Used in Traditional Chinese Medicine:
Indaconitine was traditionally used as an analgesic and anti-inflammatory agent for its pain-relieving and inflammation-reducing properties. However, due to its high toxicity, it is no longer used in modern medicine.
Used in Research and Toxicological Studies:
Indaconitine serves as a subject of interest in research and toxicological studies, providing insights into the effects of potent voltage-gated sodium channel blockers on the nervous system and muscle function. Understanding its mechanisms can contribute to the development of safer and more effective medications.

Check Digit Verification of cas no

The CAS Registry Mumber 4491-19-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,9 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4491-19:
(6*4)+(5*4)+(4*9)+(3*1)+(2*1)+(1*9)=94
94 % 10 = 4
So 4491-19-4 is a valid CAS Registry Number.
InChI:InChI=1/C34H47NO10/c1-7-35-16-31(17-40-3)21(37)13-22(41-4)34-20-14-32(39)23(42-5)15-33(45-18(2)36,25(28(34)35)26(43-6)27(31)34)24(20)29(32)44-30(38)19-11-9-8-10-12-19/h8-12,20-29,37,39H,7,13-17H2,1-6H3/t20-,21?,22?,23?,24-,25?,26?,27-,28-,29?,31?,32+,33-,34?/m1/s1

4491-19-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name indaconitine

1.2 Other means of identification

Product number -
Other names Aconitane-3,8,13,14-tetrol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1α,3α,6α,14α,16β)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4491-19-4 SDS

4491-19-4Upstream product

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