449171-85-1Relevant academic research and scientific papers
Oxa-enediynes: Probing the electronic and stereoelectronic contributions to the bergman cycloaromatization
Jones, Graham B.,Wright, Justin M.,Hynd, George,Wyatt, Justin K.,Warner, Philip M.,Huber, Robert S.,Li, Aiwen,Kilgore, Michael W.,Sticca, Robert P.,Pollenz, Richard S.
, p. 5727 - 5732 (2007/10/03)
Efficient routes to three classes of 10-membered oxa-enediynes are presented. The electronic and stereoelectronic contributions to half-lives are supported by density functional theory calculations. One member of this class cyclizes to give an isochroman which binds to and degrades the aryl hydrocarbon receptor (AhR).
