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1,2,3,4-Tetrahydro-2,6-naphthyridine dihydrochloride is a chemical compound that serves as a salt analog of 1,2,3,4-Tetrahydro-2,6-naphthyridine. It is utilized in the synthetic preparation of various pharmaceutical compounds, including quinolizidinone carboxylic acid selective M1 allosteric modulators, isoquinolinylphenyloxazolidinone antibacterials, and cyclohexanedicarboxamides as cathepsin inhibitors.

449175-43-3

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449175-43-3 Usage

Uses

Used in Pharmaceutical Synthesis:
1,2,3,4-Tetrahydro-2,6-naphthyridine dihydrochloride is used as a synthetic intermediate for the preparation of quinolizidinone carboxylic acid selective M1 allosteric modulators. These modulators have potential applications in the treatment of various neurological disorders and cognitive impairments.
Used in Antibacterial Development:
In the field of antibacterial development, 1,2,3,4-Tetrahydro-2,6-naphthyridine dihydrochloride is used as a synthetic intermediate for the preparation of isoquinolinylphenyloxazolidinone antibacterials. These compounds exhibit potent antibacterial activity against a range of bacterial pathogens, making them valuable in the development of new antibiotics.
Used in Enzyme Inhibitor Synthesis:
1,2,3,4-Tetrahydro-2,6-naphthyridine dihydrochloride is also used as a synthetic intermediate in the preparation of cyclohexanedicarboxamides as cathepsin inhibitors. Cathepsin inhibitors have potential applications in the treatment of various diseases, including cancer, by modulating the activity of cathepsin enzymes involved in cellular processes such as proteolysis and invasion.

Check Digit Verification of cas no

The CAS Registry Mumber 449175-43-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,9,1,7 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 449175-43:
(8*4)+(7*4)+(6*9)+(5*1)+(4*7)+(3*5)+(2*4)+(1*3)=173
173 % 10 = 3
So 449175-43-3 is a valid CAS Registry Number.

449175-43-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,2,3,4-Tetrahydro-2,6-naphthyridine dihydrochloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:449175-43-3 SDS

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