449186-61-2

Basic information

• Product Name: 9-[5-(morpholin-4-ylmethyl)-1H-1,2,3-triazol-1-yl]acridine
• CAS NO: 449186-61-2
• Molecular Weight: 345.404
• Mol File: 449186-61-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9-[5-(morpholin-4-ylmethyl)-1H-1,2,3-triazol-1-yl]acridine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-[5-(morpholin-4-ylmethyl)-1H-1,2,3-triazol-1-yl]acridine(449186-61-2)
• EPA Substance Registry System: 9-[5-(morpholin-4-ylmethyl)-1H-1,2,3-triazol-1-yl]acridine(449186-61-2)

Safety Data

• Hazardous Substances Data: 449186-61-2(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 266326-55-0 9-(5-chloromethyl-1H-1,2,3-triazol-1-yl)acridine 

Relevant articles and documents

Antitumour polycyclic acridines. Part 9. Synthesis of 7H-pyrido[4,3,2-kl]acridines with basic side chains

[3 + 2] Cycloaddition of 3-(dialkylamino)-1-triphenylphosphoranylidenepropan-2-ones and 9-azidoacridine affords 9-[5-(dialkylaminomethyl)-1H-1,2,3-triazol-1-yl]acridines. Graebe-Ullmann thermolysis of the triazoles has been guided by differential scanning calorimetry to predict the optimum temperature for nitrogen extrusion. Boiling diphenyl ether (bp 259°C) is a suitable solvent to convert the triazolylacridines to 2-(dialkylaminomethyl)-7H-pyrido[4,3,2-kl]acridines.