4501-60-4 Usage
Molecular Structure
1H-Pyrazole-4-carboxylic acid, 3-methyl-5-(phenylamino)-, ethyl ester is an organic compound with a pyrazole ring, a carboxyl group, a methyl group, a phenylamino group, and an ethyl ester group.
Molecular Weight
264.29 g/mol
Physical Properties
1H-Pyrazole-4-carboxylic acid, 3-methyl-5-(phenylamino)-, ethyl ester is a solid with a melting point of 94-96°C.
Solubility
It is soluble in common organic solvents such as ethanol, methanol, and acetone.
Reactivity
As an ethyl ester, it can undergo hydrolysis to form the corresponding acid. It can also react with other functional groups such as amines and alcohols in organic synthesis.
Uses
1H-Pyrazole-4-carboxylic acid, 3-methyl-5-(phenylamino)-, ethyl ester is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has potential bioactive properties and is used in the development of new drugs.
Stability
As an ethyl ester, it is more stable and easier to handle in laboratory settings, making it a popular intermediate in organic synthesis.
Medicinal Chemistry Research
Its unique structure and functional groups make it a valuable tool in medicinal chemistry research.
Check Digit Verification of cas no
The CAS Registry Mumber 4501-60-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,0 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4501-60:
(6*4)+(5*5)+(4*0)+(3*1)+(2*6)+(1*0)=64
64 % 10 = 4
So 4501-60-4 is a valid CAS Registry Number.
4501-60-4Relevant academic research and scientific papers
Reactivity of α-acylated β-enamino ketones and esters: Synthesis of pyrazoles
Missio, Lauri J.,Braibante, Hugo S.,Braibante, Mara E. F.
, p. 1243 - 1245 (2007/10/03)
The reactivity of the enamino compounds 4-amino-3-phenylamino(thio)carbonyl-3-penten-2-one 1 and 2 and ethyl 3-amino-2-phenylamino(thio)carbonyl-2-butyrate 7 and 8 was studied using the reaction with hydrazine hydrate and hydrazine hydrochloride to evaluate the 1,3 electrophilic center of the compounds by the formation of the pyrazole rings. The pyrazoles 3,4,5,9,11 and 13 were obtained depending on the reaction conditions employed.
