450368-40-8Relevant academic research and scientific papers
Covalent analogues of DNA base-pairs and triplets. Part 2: Synthesis and cytostatic activity of bis(purin-6-yl)acetylenes, -diacetylenes and related compounds
Hocek, Michal,Votruba, Ivan
, p. 1055 - 1058 (2002)
The title bis(purin-6-yl)acetylenes, -diacetylenes, -ethylenes and -ethanes were prepared as covalent base-pair analogues starting from 6-ethynylpurines and 6-iodopurines by cross-coupling and homo-coupling reactions and hydrogenations. The bis(purin-6-yl
Covalent analogues of DNA base-pairs and triplets V+. Synthesis of purine-purine and purine-pyrimidine conjugates connected by diverse types of acyclic carbon linkages
Hocek, Michal,Dvorakova, Hana,Cisarova, Ivana
, p. 1560 - 1578 (2007/10/03)
The title 1,2-bis(purin-6-yl)acetylenes, -diacetylenes, -ethylenes and -ethanes were prepared as covalent base-pair analogues starting from 6-ethynylpurines and 6-iodopurines by the Sonogashira cross-coupling or oxidative alkyne-dimerization reactions fol
