4504-12-5

Upstream product

• 100-65-2 N-Phenylhydroxylamine 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 

Downstream Products

• 64983-36-4 N-Phenylcarbamoylmalon-N,N'-dipropyldiamid 
• 64983-35-3 N-Phenylcarbamoylmalonsaeureethylesterpropylamid 
• 64983-39-7 PhNHCOCH(CONMe₂)2 
• 64983-38-6 N-Phenylcarbamoylmalonsaeureethylesterdimethylamid 
• 64983-37-5 N,N'-Di-tert-butyl-2-phenylcarbamoyl-malonamide 
• 31081-02-4 ethyl (N-t-butylcarbamoyl)(N-phenylcarbamoyl)acetate 
• 64983-34-2 N,N'dimethyl-N''-phenylmethanetricarboxamide 
• 64983-33-1 N-Phenylcarbamoylmalonsaeureethylestermethylamid 
• 54535-12-5 2-phenylaminomethylene-malonic acid monoethyl ester 

Relevant academic research and scientific papers

The Chemistry of 5-Oxodihydroisoxazoles. XIV. Synthesis of 2-(1-Aryltetrazol-5-yl)propanoic Acids

A number of N-arylisoxazol-5(2H)-ones (aryl = phenyl, isoquinolin-1-yl, quinolin-2-yl, 2-phenylquinazolin-4-yl and benzothiazol-2-yl) have been reacted with lithium azide to give 2-(1-aryltetrazol-5-yl)acetic esters, which have been C-methylated and hydrolysed.The resulting 2-(1-aryltetrazol-5-yl)propanoic acid had low antiinflammatory activity, as judged by inhibition of synthesis of prostaglandin PGE2 or tumor necrosis factor α.

The chemistry of 5-oxodihydroisoxazoles V: The photolysis of 2-phenylisoxazol-5(2H)-one ln alcohols

Ethyl 5-oxo-2-phenyl-2,5-dihydroisoxazole-4-carboxylate (1) has been photolysed in methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, t-butyl alcohol, allyl alcohol and propargyl alcohol, and the products characterised. Two types of photo products are formed: methanetricarboxylic acid derivatives resulting from alcohol capture of the first formed ketene, and 2-alkoxy-3-phenylaminoacrylates, formed by capture, by the alcohol, of the imino-carbene arising from (1) by loss of carbon dioxide.