450409-87-7 Usage
Uses
Used in Organic Synthesis:
3,5-BIS(TRIFLUOROMETHYL)PHENYLSULFONYLETHANOL is used as a versatile building block for the synthesis of various compounds. Its unique structure allows for the creation of a wide range of molecules with different properties and functions.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3,5-BIS(TRIFLUOROMETHYL)PHENYLSULFONYLETHANOL is used as a key intermediate in the development of drug molecules. The presence of trifluoromethyl groups can enhance the bioavailability and metabolic stability of these molecules, making them more effective in treating various diseases and conditions.
Used in Materials Science:
3,5-BIS(TRIFLUOROMETHYL)PHENYLSULFONYLETHANOL is also of interest in the field of materials science. It has the potential to be used in modifying the properties of polymers and other materials, leading to the development of new materials with improved characteristics and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 450409-87-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,0,4,0 and 9 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 450409-87:
(8*4)+(7*5)+(6*0)+(5*4)+(4*0)+(3*9)+(2*8)+(1*7)=137
137 % 10 = 7
So 450409-87-7 is a valid CAS Registry Number.
450409-87-7Relevant articles and documents
π-deficient 2-(arylsulfonyl)ethyl esters as protecting groups for carboxylic acids
Alonso, Diego A.,Nájera, Carmen,Varea, Montserrat
, p. 277 - 287 (2007/10/03)
Several π-deficient 2-(arylsulfonyl)ethyl groups have been studied as carboxylic acid protecting groups. The 2-[3,5-bis(trifluoromethyl)phenylsulfonyl]ethyl group is the most easily removed protecting group for acids under mild basic conditions using aqueous NaHCO3.
Simple, economical and environmentally friendly sulfone synthesis
Alonso, Diego A.,Nájera, Carmen,Varea, Montserrat
, p. 3459 - 3461 (2007/10/03)
Chemoselective sulfur oxidation of functionalized sulfides was developed using catalytic amounts of MnSO4·H2O (1 mol%) and 30% H2O2 in the presence of a buffer solution of NaHCO3. Aromatic and aliphatic sulfides were oxidized to sulfones in quantitative yields in 15 min. Different functional groups including double bonds, alcohols, ethers of THP and TBDMS groups were tolerated under these mild and green reaction conditions.
