Welcome to LookChem.com Sign In|Join Free

CAS

  • or

450410-87-4

11,12-O-didehydrocarnosol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

450410-87-4 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 450410-87-4 Structure

  • Basic information

    1. Product Name: 11,12-O-didehydrocarnosol
    2. Synonyms: 11,12-O-didehydrocarnosol
    3. CAS NO:450410-87-4
    4. Molecular Formula:
    5. Molecular Weight: 328.408
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 450410-87-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 11,12-O-didehydrocarnosol(CAS DataBase Reference)
    10. NIST Chemistry Reference: 11,12-O-didehydrocarnosol(450410-87-4)
    11. EPA Substance Registry System: 11,12-O-didehydrocarnosol(450410-87-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 450410-87-4(Hazardous Substances Data)

450410-87-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 450410-87-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,0,4,1 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 450410-87:
(8*4)+(7*5)+(6*0)+(5*4)+(4*1)+(3*0)+(2*8)+(1*7)=114
114 % 10 = 4
So 450410-87-4 is a valid CAS Registry Number.

450410-87-4Upstream product

450410-87-4Downstream Products

450410-87-4Relevant articles and documents

Unexpected oxidation of ortho-phenol groups of carnosol with m-chloroperbenzoic acid

Marrero, Joaquín G.,San Andrés Tejera, Lucía,Luis, Javier G.,Rodríguez, Matías L.

, p. 1517 - 1519 (2002)

The oxidation reaction of carnosol (2) with m-chloroperbenzoic acid and sodium bicarbonate in dichloromethane gave an abietane diterpene (3) with an anhydride function on C ring. The conversion can be rationalized by a Baeyer-Villiger reaction from the initially generated ortho-quinone. The structure of this anhydride was confirmed by spectroscopic and X-ray crystallographic analysis. This reaction could be an important key step towards the synthesis of natural products such us drimane sesquiterpenes.

Cytotoxicity of abietane diterpenoids from Perovskia abrotanoides and of their semisynthetic analogues

Aoyagi, Yutaka,Takahashi, Yoshinao,Satake, Yudai,Takeya, Koichi,Aiyama, Ritsuo,Matsuzaki, Takeshi,Hashimoto, Shusuke,Kurihara, Teruo

, p. 5285 - 5291 (2006)

Seven known abietane diterpenoids and 11-O- and 12-O-acetylcarnosic acids were isolated from a methanol extract of Perovskia abrotanoides (Labiatae). Structure and cytotoxic activity relationships (SAR) of the natural and semisynthetic analogues of the presently isolated abietane diterpenoids were studied by using P388 murine leukemia cells.

Inhibition of squalene synthase of rat liver by abietane diterpenes derivatives

Macías-Alonso, Mariana,Andrés, Lucía S.,Córdova-Guerrero, Iván,Estolano-Cobián, Arturo,Díaz-Rubio, Laura,Marrero, Joaquín G.

supporting information, p. 2972 - 2976 (2019/11/11)

In the current study, chemical composition of cultivated Salvia canariensis L was determined. Carnosol was the main product isolated. We prepared more lipophilic derivatives from carnosol, and both isolated and semisynthetic abietane diterpenes were evaluated in?vitro as inhibitors of squalene synthase. Among the compounds tested, carnosol was the most potent inhibitor (IC50 = 17.6 μM). These results highlight the great potential of this species for the production of new ingredients in nutritional supplements for the treatment of hyperlipidemia.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 450410-87-4