451494-79-4

Upstream product

• 451494-78-3 [1-(1,1-dimethyl-2-propynyl)-4-piperidinyl]dimethylamine 
• 451494-38-5 7-bromo-N⁴-(3-chloro-4-fluorophenyl)quinazoline-4,6-diamine 

Downstream Products

• 451493-22-4 C₂₉H₃₂ClFN₆O 

Relevant academic research and scientific papers

Quinazoline derivatives

A compound of the formula (I) or a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, an optically active compound thereof, a racemate thereof or a diastereomer mixture thereof has a superior tyrosine-specific protein kinase inhibitory activity and is useful as a pharmaceutical agent, particularly as an agent for the prophylaxis or treatment of various cancers, psoriasis or diseases caused by arteriosclerosis, and the like.