4517-99-1

Usage

Uses

Used in Pharmaceutical Research and Development:
(5H-Dibenzo[a,d]cyclohepten-5-ylidene)acetic acid is used as a research compound for its potential anti-inflammatory and anti-cancer properties, making it a candidate for drug development in these therapeutic areas.
Used in Neurological Disorder Treatment:
In the field of neurology, (5H-Dibenzo[a,d]cyclohepten-5-ylidene)acetic acid is used as a potential treatment for various neurological disorders, such as Alzheimer's disease and schizophrenia, due to its studied effects on neurotransmitter systems in the brain.

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 2222-33-5 dibenzosuberenon 
• 15181-07-4 1-heptyl-4-methyl-benzene 
• 688-49-3 ethyl (diethoxyphosphino)acetate 
• 28002-96-2 ethyl dibenzocycloheptatrienylideneacetate 

Downstream Products

• 1195760-33-8 N-(2-amino-phenyl)-6-[2-(2-dibenzo[a,d]cyclohepten-5-ylidene-acetylamino)-ethylamino]-nicotinamide 

Relevant academic research and scientific papers

NOVEL DIARYLALKENE DERIVATIVES AND NOVEL DIARYLALKANE DERIVATIVES

The invention relates to a compound represented by the following general formula (1) or its analogue, which selectively inhibit N-type calcium channels or its analogue, and to a method for treating pain etc. comprising the compound represented by the following general formula (1) or its analogue to a patient in need of such treatment: wherein, A represents CH=CH, etc., a, b, c and d represents CH etc., R1, R2, R3, R4, R5 and R6 represents H etc., V--W represents C=C, etc., n represents 0 to 3, Y1 represents O etc., B represents--(CH2)vCHR21 wherein v is 0 to 3, R21 represents H, a lower alkyl group or the like, etc., G represents--CO--, a covalent bond, etc., m is 0 to 6, R7 and R8 represents H, a lower alkyl group,--COR18a,--COOR20 wherein R18a and R20 each represents a lower alkyl group or the like, etc.

MEDICINAL COMPOSITIONS CONTAINING GABAPENTIN OR PREGABALIN AND N-TYPE CALCIUM CHANNEL ANTAGONIST

The present invention relates to a pharmaceutical composition useful for preventing/treating pain, which comprises combination of gabapentin or pregabalin, or pharmaceutically acceptable salts thereof and N-type calcium channel antagonists or pharmaceutically acceptable salts thereof such as a compound having the following structure.

DIRECT OBSERVATION AND TRANSFORMATIONS OF DICATIONS DERIVED FROM DIBENZOTROPYLIUM IONS

Carboxylic acid 1 and its derivatives 2, 3 treated with triflic acid below -20 deg C afford the dications 1H2(2+) - 3H2(2+).Cyclodehydration above 20 deg C (or in the gas-phase, CIMS of 3) leads to the diprotonated ketone 4H2(2+).Key Words: Chemical ioniz

Method for modulating the immune response with dibenzocycloheptenylidenes

A method of modulating the immune response in mammals by administering thereto compounds having the general formula: STR1 where R is hydrogen or alkyl of 1-4 carbon atoms, R1 is hydrogen or an alkyl of 1-4 carbon atoms and pharmaceutically acceptable salts thereof.