452057-00-0Relevant articles and documents
Pyridinylimidazoles as dual glycogen synthase kinase 3β/p38α mitogen-activated protein kinase inhibitors
Heider, Fabian,Ansideri, Francesco,Tesch, Roberta,Pantsar, Tatu,Haun, Urs,D?ring, Eva,Kudolo, Mark,Poso, Antti,Albrecht, Wolfgang,Laufer, Stefan A.,Koch, Pierre
, p. 309 - 329 (2019/05/15)
Compounds simultaneously inhibiting two targets that are involved in the progression of the same complex disease may exhibit additive or even synergistic therapeutic effects. Here we unveil 2,4,5-trisubstituted imidazoles as dual inhibitors of p38α mitoge