452094-39-2Relevant articles and documents
Benzene and dopamine catechol quinones could initiate cancer or neurogenic disease
Zahid, Muhammad,Saeed, Muhammad,Rogan, Eleanor G.,Cavalieri, Ercole L.
experimental part, p. 318 - 324 (2011/01/03)
Catechol quinones of estrogens react with DNA by 1,4-Michael addition to form depurinating N3Ade and N7Gua adducts. Loss of these adducts from DNA creates apurinic sites that can generate mutations leading to cancer initiation. We compared the reactions o