452282-75-6Relevant academic research and scientific papers
Structure-activity relationships of the ultrapotent vanilloid resiniferatoxin (RTX): The homovanillyl moiety
Appendino, Giovanni,Ech-Chahad, Abdellah,Minassi, Alberto,Bacchiega, Sara,Petrocellis, Luciano De,Marzo, Vincenzo Di
, p. 132 - 135 (2007/10/03)
Starting from ROPA (2), analogues of RTX (1a) modified on the acyl side chain were prepared and evaluated for vanilloid activity in HEK-293 cells over-expressing the human recombinant TRPV1. The ROPA motif provided an enhancement of potency sufficient to
BENZO(b)FURAN DIMERS
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Page 24, (2010/02/06)
Benzo[b]furan dimers and processes for their preparation are provided. The invention provides a synthetic process for the preparation of benzo[b]furan dimer using mild reaction conditions, which provides a high substituent tolerance and is appropriate for
