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452337-37-0

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452337-37-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 452337-37-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,2,3,3 and 7 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 452337-37:
(8*4)+(7*5)+(6*2)+(5*3)+(4*3)+(3*7)+(2*3)+(1*7)=140
140 % 10 = 0
So 452337-37-0 is a valid CAS Registry Number.

452337-37-0Downstream Products

452337-37-0Relevant articles and documents

Compositions and methods for enhancing drug delivery across and into epithelial tissues

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Page column 45, (2010/02/07)

This invention provides compositions and methods for enhancing delivery of drugs and other agents across epithelial tissues, including the skin, gastrointestinal tract, pulmonary epithelium, ocular tissues and the like. The compositions and methods are also useful for delivery across endothelial tissues, including the blood brain barrier. The compositions and methods employ a delivery enhancing transporter that has sufficient guanidino or amidino sidechain moieties to enhance delivery of a compound conjugated to the reagent across one or more layers of the tissue, compared to the non-conjugated compound. The delivery-enhancing polymers include, for example, poly-arginine molecules that are preferably between about 6 and 25 residues in length.

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