452338-89-5Relevant academic research and scientific papers
Asymmetric carbon-carbon bond formations by conjugate additions of lithiated N-Boc allylic amines to nitroalkenes: Enantioselective synthesis of functionalized cyclopentanoids
Johnson, Timothy A.,Curtis, Michael D.,Beak, Peter
, p. 2747 - 2749 (2002)
(Matrix presented) Allylic organolithiums generated by enantioselective deprotonation of N-Boc-N-(p-methoxyphenyl) allylic amines undergo conjugate additions with nitroalkenes to provide enecarbamates containing two contiguous stereogenic centers in good
Asymmetric carbon-carbon bond formations in conjugate additions of lithiated N-Boc allylic and benzylic amines to nitroalkenes: Enantioselective synthesis of substituted piperidines, pyrrolidines, and pyrimidinones
Johnson, Timothy A.,Jang, Doo Ok,Slafer, Brian W.,Curtis, Michael D.,Beak, Peter
, p. 11689 - 11698 (2007/10/03)
(-)-Sparteine mediated lithiations of N-Boc-allylic and benzylic amines provide configurationally stable intermediates which on conjugate additions to nitroalkenes provide highly enantioenriched enecarbamate products in good yields, and with high diastere
