452339-71-8

Basic information

• Product Name: CarbaMic acid, [2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-diMethylethyl ester
• Synonyms: CarbaMic acid, [2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-diMethylethyl ester;tert-Butyl N-(2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl)carbamate;tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethylcarbamate;tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl;tert-Butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate
• CAS NO: 452339-71-8
• Molecular Formula: C₁₇H₂₃NO₅
• Molecular Weight: 321.36822
• Product Categories: Intermediate
• Mol File: 452339-71-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 489.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.134±0.06 g/cm3(Predicted)
• PKA: 10.92±0.46(Predicted)
• CAS DataBase Reference: CarbaMic acid, [2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: CarbaMic acid, [2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-diMethylethyl ester(452339-71-8)
• EPA Substance Registry System: CarbaMic acid, [2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-diMethylethyl ester(452339-71-8)

Safety Data

• Hazardous Substances Data: 452339-71-8(Hazardous Substances Data)

Usage

General Description

CarbaMic acid, [2-(2,2-diMethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyl]-, 1,1-diMethylethyl ester is a chemical compound with the molecular formula C19H22O6. It is an ester of carbaMic acid, a compound that contains a carbamic acid group. The compound contains a 2-oxoethyl group and a 2,2-dimethyl-4H-1,3-benzodioxin-6-yl group, which are attached to the carbaMic acid moiety. This chemical may be used in pharmaceuticals, research, or other industrial applications. However, it is important to handle this compound with care, as it may have potential health and safety hazards associated with it.

Upstream product

• 77-76-9 2,2-dimethoxy-propane 
• 1761-61-1 5-bromosalicyclaldehyde 
• 2316-64-5 5-bromo-2-hydroxybenzyl alcohol 
• 52113-69-6 6-bromo-2,2-dimethyl-4H-benzo[1,3]dioxine 
• 54030-34-1 1-(2,2-dimethyl-4H-benzo[d][1,3]dioxan-6-yl)ethanone 
• 102293-80-1 2-bromo-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethanone 
• 51779-32-9 iminodicarboxylic acid di-tert-butyl ester 
• 452339-70-7 di-(tert-butyl) 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-oxoethyliminodicarbonate 

Downstream Products

• 503068-36-8 (5R)-3-{6-[(2-{[(2,6-dichlorophenyl)methyl]oxy}ethyl)oxy]-hexyl}-5-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-one 
• 503068-37-9 (2R)-hydroxy-2-(2,2-dimethyl-4Η-1,3-benzodioxole-6-yl)-N-3-[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexyl]-ethylamine 
• 503068-34-6 4-[(1R)-2-({6-[(2-{[(2,6-dichlorophenyl)methyl]oxy}ethyl)oxy]-hexyl}-amino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol 
• 590410-68-7 (5R)-5-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-3-[6-(4-phenylbutoxy)hexyl]-1,3-oxazolidin-2-one 
• 452339-73-0 (5R)-5-(2,2-dimethyl- 4H-1,3-benzodioxin-6-yl)-1,3-oxazolidin-2-one 
• 590410-69-8 (R)-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-(6-(4-phenylbutoxy)hexylamino)ethanol 
• 135271-47-5 (R)-(-)-salmeterol 
• 452339-72-9 tert-butyl (2R)-2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-hydroxyethylcarbamate 

Relevant articles and documents

Preparation method for synthesizing vilanterol intermediate by catalysis with modified graphene

The invention discloses a method for synthesizing a vilanterol intermediate tert-butyl 2-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-carbonylethylcarbamate by catalysis with modified reduced graphene oxide with a high carboxylation edge, and belongs to the technical field of organic catalysis. The method utilizes an acidic catalytic reaction of the relatively large amount of carboxyl groups at the edge of reduced graphene oxide to overcome the disadvantage that an adopted organic strong acid is difficult to recover in the prior art, solve the problem of heterogeneous phase and difficult recyclingapplication of a catalyst, and reduce environmental protection pressure. The catalytic synthesis method adopting graphene is environmentally friendly, and meets requirements of modern green industrial production.

Phenylethanolamine derivative and its preparation method and application

The invention relates to a phenylethanolamine derivative represented in the following formula 1. The phenylethanolamine derivative can serve as a beta 2 receptor agonist. The formula can be seen from the description.

PHENETHANOLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF RESPIRATORY DISEASES

The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.