452927-96-7Relevant academic research and scientific papers
Sulfinyl group as an intramolecular nucleophile: Synthesis of bromohydrins from β-methyl-γ,δ-unsaturated sulfoxides with high 1,2-asymmetric induction
Raghavan, Sadagopan,Reddy, S. Ramakrishna,Tony,Kumar, Ch. Naveen,Varma, Ashok K.,Nangia, Ashwini
, p. 5838 - 5841 (2002)
Bromohydrins have been prepared from β-methyl-γ,δ-unsaturated sulfoxides with high regio- and stereoselectivity. The reaction proceeds via neighboring group participation of the sulfinyl moiety with inversion of sulfoxide configuration as proven by an 18O labeling study and x-ray crystallography.
