453547-64-3Relevant academic research and scientific papers
Design, synthesis and biological evaluation of novel 1α,25- dihydroxyvitamin D3 analogues possessing aromatic ring on 2α-position
Honzawa, Shinobu,Hirasaka, Koshiro,Yamamoto, Yasuhiro,Peleg, Sara,Fujishima, Toshie,Kurihara, Masaaki,Saito, Nozomi,Kishimoto, Seishi,Sugiura, Takayuki,Waku, Keizo,Takayama, Hiroaki,Kittaka, Atsushi
, p. 11253 - 11263 (2007/10/03)
In the present study, we describe the synthesis of new analogues of 1α,25-dihydroxyvitamin D3 (1), which possess hydrophobic aromatic ring on the 2α position. Among these analogues, 2α-benzyl analogue showed the highest potency in the affinity
