453556-98-4Relevant academic research and scientific papers
Synthesis of functionalised bipyridines by sequential nucleophilic substitution of hydrogen and cycloaddition in 1,2,4-triazine rings
Kozhevnikov, Dmitry N.,Kozhevnikov, Valery N.,Nikitina, Tatiana V.,Rusinov, Vladimir L.,Chupakhin, Oleg N.,Neunhoeffer, Hans
, p. 30 - 32 (2007/10/03)
A new methodology for the synthesis of functionalised bipyridines by the direct cyanation of 3-(2-pyridyl)-1,2,4-triazine 4-oxide through nucleophilic substitution for hydrogen followed by the transformation of the 1,2,4-triazine ring into the pyridine ring by the Diels-Alder reaction and, finally, the chemical conversion of the cyano group is described.
