453563-01-4

Upstream product

• 99-88-7 4-Isopropylaniline 
• 100973-67-9 ethyl 4-(benzylamino)-2-(methylthio)pyrimidine-5-carboxylate 
• 686267-34-5 4-(benzylamino)-2-(methylsulfanyl)pyrimidine-5-carboxylic acid 

Downstream Products

• 453563-00-3 N-[4-(isopropyl)-phenyl]{4-[(4-pyridylmethyl)-amino]-pyrimidin-5-yl}-carboxamide 

Relevant academic research and scientific papers

Substituted alkylamine derivatives and methods of use

Selected heterocyclic compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Substituted alkylamine derivatives and methods of use

Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.