454219-18-2Relevant academic research and scientific papers
Potent and selective, sulfamide-based human β3-adrenergic receptor agonists
Dow, Robert L.,Paight, Ernest S.,Schneider, Steven R.,Hadcock, John R.,Hargrove, Diane M.,Martin, Kelly A.,Maurer, Tristan S.,Nardone, Nancy A.,Tess, David A.,DaSilva-Jardine, Paul
, p. 3235 - 3240 (2007/10/03)
A series of sulfamide-based analogs related to L-796568 were prepared and evaluated for their biological activity at the human β3- adrenergic receptor (AR). This modification allows for a significant reduction in molecular weight, while maintai
Beta3 agonists and uses thereof
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, (2008/06/13)
Sulfamide compounds having formula (I) are described as well as their use in the treatment of diseases dependent on the signaling pathways associated with β-adrenergic receptors, such as obesity, diabetes, hypertension, gastrointestinal hypo- or hyper-mot
