454251-74-2Relevant academic research and scientific papers
A novel synthesis of enantiopure octahydropyrrolo[3,4-b]pyrroles by intramolecular [3 + 2] dipolar cycloaddition on chiral perhydro-1,3-benzoxazines
Pedrosa, Rafael,Andres, Celia,De Las Heras, Laura,Nieto, Javier
, p. 2513 - 2516 (2002)
(Matrix presented) Condensation of N-substituted glycines with chiral 3-allyl-2-formyl perhydro-1,3-benzoxazines forms an azomethine ylide that cyclizes to give octahydropyrrolo[3,4-b]pyrrole derivatives. The [3 + 2] dipolar cycloadditions are stereoespec
