454431-85-7Relevant academic research and scientific papers
Ruthenium Carbene-Mediated Construction of Strained Allenes via the Enyne Cross-Metathesis/Cyclopropanation of 1,6-Enynes
Gao, Ming,Gao, Qiangqiang,Hao, Xiangbin,Wu, Ying,Zhang, Qingmin,Liu, Guohua,Liu, Rui
supporting information, p. 1139 - 1143 (2020/02/15)
Herein, we report on the unprecedented dimerization of 1,6-enynes using a commercially available ruthenium complex RuCl2(PPh3)3, which results in a series of bicyclo[3.1.0]hexyl allene derivatives in moderate to excellent yields. Mechanistic investigation indicates that the in-situ-generated ruthenium vinylidene undergoes a site-selective metathesis process to provide allenyl ruthenium carbene, which can be intramolecularly trapped by the pendent C=C bond of enyne through a [2 + 2] cycloaddition/metal elimination process.
Diastereoselective cascade synthesis of azabicyclo[3.1.0]hexanes from acyclic precursors
Boehmer, Jutta,Grigg, Ronald,Marchbank, John D.
, p. 768 - 769 (2007/10/03)
The diastereoselective synthesis of azabicyclo[3.1.0]hexanes bearing different substituents on all positions of the cyclopropane ring has been achieved in moderate to good yields.
