454439-60-2

Upstream product

• 454439-58-8 ethyl 2-[4-(benzyloxy)butyl]acrylate 
• 60789-54-0 4-bromobutyl benzyl ether 
• 5817-26-5 ethyl (2S)-pyrrolidine-2-carboxylate 
• 454439-59-9 2-[4-(benzyloxy)butyl]acrylic acid 

Downstream Products

• 454439-62-4 (3S,8aS)-3-(4-Benzyloxy-butyl)-3-bromomethyl-tetrahydro-pyrrolo[2,1-c][1,4]oxazine-1,4-dione 
• 454439-63-5 (3S,8aS)-3-[4-(benzyloxy)butyl]-3-methyltetrahydro-1H-pyrrolo[2,1-c][1,4]oxazine-1,4(3H)-dione 
• 454439-64-6 (2S)-6-(benzyloxy)-2-hydroxy-2-methylhexanoic acid 
• 454439-66-8 benzyl 4-[(4S)-2,2,4-trimethyl-1,3-dioxolan-4-yl]butyl ether 
• 454439-65-7 (2S)-6-(benzyloxy)-2-methyl-1,2-hexanediol 
• 454439-61-3 (2S)-1-{2-[4-(benzyloxy)butyl]acryloyl}pyrrolidine-2-carboxylic acid 

Relevant academic research and scientific papers

Asymmetric synthesis of (S)-4-(2,2,4-trimethyl-1,3-dioxolan-4-yl)-1-butanol, a key intermediate for (1S,5R)-(-)-frontalin via asymmetric bromolactonization

A asymmetric synthesis of (S)-4-(2,2,4-trimethyl-1,3-dioxolan-4-yl)-1-butanol, a key intermediate for (1S,5R)-(-)-frontalin, via asymmetric bromolactonization employing (S)-(-)-proline as a chiral auxiliary is described.