454479-35-7

Basic information

• Product Name: 1-(4-benzyloxy-phenyl)-4-(4-nitro-phenyl)-piperazine
• Synonyms: 1-(4-benzyloxy-phenyl)-4-(4-nitro-phenyl)-piperazine
• CAS NO: 454479-35-7
• Molecular Weight: 389.454
• Mol File: 454479-35-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-benzyloxy-phenyl)-4-(4-nitro-phenyl)-piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-benzyloxy-phenyl)-4-(4-nitro-phenyl)-piperazine(454479-35-7)
• EPA Substance Registry System: 1-(4-benzyloxy-phenyl)-4-(4-nitro-phenyl)-piperazine(454479-35-7)

Safety Data

• Hazardous Substances Data: 454479-35-7(Hazardous Substances Data)

Upstream product

• 110-85-0 piperazine 
• 6793-92-6 p-benzyloxyphenylbromide 
• 586-78-7 para-nitrophenyl bromide 

Downstream Products

• 184177-84-2 4-[4-(4-benzyloxy-phenyl)-piperazin-1-yl]-phenylamine 
• 74853-08-0 1-(4-aminophenyl)-4-(4-hydroxyphenyl)piperazine 

Relevant articles and documents

Mono N-arylation of piperazine(III): Metal-catalyzed N-arylation and its application to the novel preparations of the antifungal posaconazole and its advanced intermediate

A novel application of Pd0-catalyzed arylation to mono N-arylated piperazines, its mechanism, and its application towards the novel syntheses of the key differentially N,N′-diarylated piperazine antifungal intermediate N-(4-hydroxyphenyl)-N′-(4-aminophenyl)piperazine 5 as well as posaconazole 1 are described.