454709-94-5Relevant articles and documents
Gadolinium complexes of highly rigid, open-chain ligands containing a cyclobutane ring in the backbone: Decreasing ligand denticity might enhance kinetic inertness
Porcar-Tost, Oriol,Olivares, José A.,Pallier, Agnès,Esteban-Gómez, David,Illa, Ona,Platas-Iglesias, Carlos,Tóth, éva,Ortu?o, Rosa M.
, (2019/10/10)
In an effort to explore novel ligand scaffolds for stable and inert lanthanide complexation in magnetic resonance imaging contrast agent research, three chiral ligands containing a highly rigid (1S,2S)-1,2-cyclobutanediamine spacer and different number of
Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
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, (2008/06/13)
The present invention relates to substituted xanthines of general formula wherein R1 to R4 are defined as in claim 1, the tautomers and the stereoisomers thereof, mixtures thereof, the prodrugs and the salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).