455-20-9 Usage
General Description
p-Ethylbenzenesulphonyl fluoride is a chemical compound that belongs to the sulphonyl fluoride family. It is commonly used as a reagent in organic synthesis, particularly for the introduction of the sulphonyl fluoride functional group into organic molecules. p-ethylbenzenesulphonyl fluoride is known for its ability to efficiently and selectively react with nucleophiles, such as alcohols, amines, and thiols, to form the corresponding sulphonyl fluoride derivatives. It is also utilized in the preparation of various pharmaceuticals and agrochemicals, as well as in the synthesis of other functional materials. Additionally, p-ethylbenzenesulphonyl fluoride has been investigated for its potential use as a reagent in bioconjugation and chemical biology applications. Overall, this compound is a versatile and valuable tool in organic chemistry and chemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 455-20-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,5 and 5 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 455-20:
(5*4)+(4*5)+(3*5)+(2*2)+(1*0)=59
59 % 10 = 9
So 455-20-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H9FO2S/c1-2-7-3-5-8(6-4-7)12(9,10)11/h3-6H,2H2,1H3
455-20-9Relevant articles and documents
Copper-catalyzed three-component reaction of arylhydrazine hydrochloride, DABSO, and NFSI for the synthesis of arenesulfonyl fluorides
Chen, Qing-Yun,Guo, Yong,Hu, Xiaojun,Liu, Chao,Liu, Yongan,Ma, Xiaoyu,Pan, Qijun,Pang, Wan,Wu, Jingjing
supporting information, p. 8999 - 9003 (2021/11/04)
This paper reports a convenient copper-catalyzed three-component conversion of arylhydrazine hydrochlorides to arenesulfonyl fluorides in good yields under mild conditions, using 1,4-diazabicyclo [2.2.2]octane bis(sulfur dioxide) (DABSO) as a sulfonyl source andN-fluorobenzenesulfonimide (NFSI) as a fluorine source based on a radical sulfur dioxide insertion and fluorination strategy. Notably, arylhydrazine hydrochloride is used as a safe precursor of aryl radicals.
NATHAN-BAKER EFFECTS IN THE HETEROGENEOUS SULFONATION OF ALKYLBENZENES
Krylov, E. N.,Khokhlova, S. G.
, p. 341 - 343 (2007/10/02)
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