4550-52-1 Usage
Structure
Contains a 1,3,5-triazine ring, a chlorine atom, a cyclohexyl group, and a methoxy group
Applications
a. Pharmaceutical synthesis and production
b. Agrochemical synthesis and production
Potential uses
a. Treatment of cancer and other diseases (medicinal chemistry)
b. Herbicidal properties (agricultural industry)
c. Pesticidal properties (agricultural industry)
Safety
Should be handled with caution and in accordance with proper safety protocols due to potential health and environmental hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 4550-52-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,5 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4550-52:
(6*4)+(5*5)+(4*5)+(3*0)+(2*5)+(1*2)=81
81 % 10 = 1
So 4550-52-1 is a valid CAS Registry Number.
4550-52-1Relevant academic research and scientific papers
Aminopyrimidinone Cdc7 Kinase Inhibitors
Woods, Keith W.,Lai, Chunqiu,Miyashiro, Julie M.,Tong, Yunsong,Florjancic, Alan S.,Han, Edward K.,Soni, Niru,Shi, Yan,Lasko, Loren,Leverson, Joel D.,Johnson, Eric F.,Shoemaker, Alexander R.,Penning, Thomas D.
supporting information; scheme or table, p. 1940 - 1943 (2012/04/17)
We have investigated the SAR of a series of pyrimidinone-containing Cdc7 kinase inhibitors. A wide range of amine substitutions give potent compounds with activities (Ki) less than 1 nM. Kinase selectivity is reasonable and cytotoxicity corresponds to inhibition of MCM2 phosphorylation.