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9-chloro-4-[N-(3-(N-([1,10]phenanthrolin-5-yl)-N-(p-toluenesulfonyl)amino)propyl)carboxamido]acridine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

455251-65-7

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455251-65-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 455251-65-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,5,2,5 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 455251-65:
(8*4)+(7*5)+(6*5)+(5*2)+(4*5)+(3*1)+(2*6)+(1*5)=147
147 % 10 = 7
So 455251-65-7 is a valid CAS Registry Number.

455251-65-7Downstream Products

455251-65-7Relevant academic research and scientific papers

Design of site specific DNA damaging agents for generation of multiply damaged sites

Martelli, Alain,Constant, Jean-Francois,Demeunynck, Martine,Lhomme, Jean,Dumy, Pascal

, p. 4291 - 4298 (2007/10/03)

We describe the synthesis and DNA damaging activities of hybrid molecules in which a purine (adenine) is linked to an intercalating chromophore (acridine) by a polyamino linker. A DNA damaging agent, phenanthroline or para-nitrobenzamide, is tethered to the acridine moiety at various positions. Our goal is to induce upon activation other lesions in close proximity to the abasic site and therefore create cytotoxic multiply damaged sites.

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