455252-86-5

Upstream product

• 455252-81-0 (S)-4-{2-[(1S,2S,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,6,6-trimethyl-bicyclo[3.1.1]hept-2-yl]-ethyl}-2,4-dimethyl-cyclohex-2-enone 
• 455252-80-9 tert-Butyl-{(1S,2S,4S,5S)-4-[2-((R)-3-ethyl-1-methyl-cyclopent-2-enyl)-ethyl]-4,6,6-trimethyl-bicyclo[3.1.1]hept-2-yloxy}-dimethyl-silane 
• 455252-88-7 (R)-8-[(1S,2S,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,6,6-trimethyl-bicyclo[3.1.1]hept-2-yl]-6-methyl-octan-3-ol 
• 455252-79-6 (R)-8-[(1S,2S,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,6,6-trimethyl-bicyclo[3.1.1]hept-2-yl]-6-methyl-octan-3-one 
• 455252-83-2 Dithiocarbonic acid O-{(1S,2S,4S,5S)-4-[2-((S)-1,3-dimethyl-4-oxo-cyclohex-2-enyl)-ethyl]-4,6,6-trimethyl-bicyclo[3.1.1]hept-2-yl} ester S-methyl ester 
• 455252-77-4 tert-Butyl-[(1S,2S,4S,5S)-4-((S)-3,7-dimethyl-oct-6-enyl)-4,6,6-trimethyl-bicyclo[3.1.1]hept-2-yloxy]-dimethyl-silane 
• 455252-78-5 (R)-6-[(1S,2S,4S,5S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,6,6-trimethyl-bicyclo[3.1.1]hept-2-yl]-4-methyl-hexanal 
• 455252-82-1 (S)-4-[2-((1S,2S,4S,5S)-4-Hydroxy-2,6,6-trimethyl-bicyclo[3.1.1]hept-2-yl)-ethyl]-2,4-dimethyl-cyclohex-2-enone 
• 455252-76-3 (1S,4S,5S)-4-((S)-3,7-Dimethyl-oct-6-enyl)-4,6,6-trimethyl-bicyclo[3.1.1]heptan-2-one 
• 455252-84-3 (S)-4-[2-((1S,6R)-6-Isopropyl-1-methyl-cyclohex-3-enyl)-ethyl]-2,4-dimethyl-cyclohex-2-enone 
• 55314-73-3 (S)-citronellyl magnesium bromide 
• 455252-85-4 (3S,4R)-3-[2-((S)-1,3-Dimethyl-4-oxo-cyclohex-2-enyl)-ethyl]-4-isopropyl-3-methyl-hexanedial 

Relevant academic research and scientific papers

Progress towards the total synthesis of guanacastepene A. Approaches to the construction of quaternary carbons and the 5-7-6 tricyclic carbon skeleton

The construction of the 5-7-6 tricyclic skeleton of guanacastepene A, including the quaternary carbons, has been achieved. The C-11 and C-8 quaternary carbons were constructed by cuprate addition and carbene insertion, respectively. The 5-7-6 tricyclic core was generated by a selective aldol and SmI2-induced intramolecular aldehyde-alkene coupling.