455253-68-6Relevant academic research and scientific papers
3,4-Disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. exploring P2 elements for selectivity
Setti, Eduardo L.,Davis, Dana,Chung, Tobee,McCarter, John
, p. 2051 - 2053 (2007/10/03)
A novel series of 3,4-disubstituted azetidinones based inhibitors of the cysteine protease cathepsin K (Cat K) has been identified. Although not optimized, some of these compounds show at least 100-fold selectivity against other cathepsins. The use of cyc
